চার্কোট-মেরি-টুথ ডিজিজ কী… সেই বিধ্বংসী রোগ যা ন্যাশভিলকে হত্যা করেছে 9-1-1 অভিনেত্রী ইসাবেল টেট
Nashville’s 9-1-1 actress, who died at age 23, suffered from a neurological disorder affecting 3 million people worldwide, her family has said. Isabel Tate’s death was revealed Thursday, with her family saying she died Sunday from Charcot-Marie-Tooth disease, or CMT, a genetic condition that causes the peripheral nerves, such as those in the hands or feet, to slowly degenerate over time. The disease causes muscle weakness in the legs and arms, with doctors saying sufferers have difficulty moving their limbs before losing sensation in those areas. The disease is not fatal for most patients, however. In rare cases, though, it can affect the muscles needed for breathing, slowly depriving someone of oxygen. Tate’s family said their daughter had a particularly aggressive form of the disease. In a 2022 Instagram post, Tate opened up about her illness, revealing how her condition had “really progressed.” She said: “When I was 13, I was diagnosed with a progressive neuromuscular disease that causes the muscles in my feet to weaken over time. Over the years, I continued to live my life and noticed little things became more difficult for me, but not so much where they impacted me.” Isabel Tate’s obituary described her as someone who “wanted to change the world” and was “full of fire.” Your browser does not support iframes. She continued: “Recently, the disease has progressed significantly and I came to the conclusion that I need to use a wheelchair occasionally if I want to live my life to the fullest.” It has been a hard journey for me as it was difficult to accept help and surrender to the progression of this condition. “CMT is considered a rare disease, but it is one of the most common inherited neurological disorders, affecting 1 in 2,500 people in the United States and 3 million worldwide. Named for the three doctors who described the disease in 1886, Jean-Martin Charcot, Pierre Marie and Howard Henry Tooth, association sub data 1 more identified. Charcot-Marie-Tooth, all caused by genetic mutations that prevent proteins needed for nerves to function correctly. Among the most common are CMT1, in which the fatty sheaths that insulate the nerves break down, resulting in cell damage, and CMT2, which affects the nerve fibers that transmit impulses from the nerve cell body to muscles and sensory organs. Among the most devastating forms is CMT type 4J, which is caused by a mutation in the FIG4 gene, which nutrients in nerve cells that are important for transit control. This type of disease can progress rapidly and cause respiratory complications, with many patients dying in childhood. It was unclear what type Tate had. Isabel Tate graduated from Middle Tennessee State University with a degree in economics. Isabel Tate played the role of Julie in the pilot episode of the Len Rhimes-hosted show 9-1-1 Nashville; pictured above In patients with the condition, a diagnosis is usually made between the ages of five and 15, when symptoms begin to present. Early warning signs include an unusually clumsy or accident-prone appearance, difficulty walking, and having the toe drop forward when someone lifts their foot. In later stages, patients suffer from weak muscles and numbness in their arms and legs. They may also have cold hands and feet from poor circulation and regularly feel fatigued due to the extra exertion required to move. Doctors diagnose the disease using a physical examination for muscle weakness, a nerve conduction test, and a genetic test. There is no cure for the disease, but treatments are available to help reduce the symptoms of the condition. Many patients will be given physical therapy to strengthen muscles and reduce the risk of unwanted contractions. Patients may also get walking aids, such as insoles for their shoes and therapies can help them identify areas of their life where they are struggling. Country singer Alan Jackson has also revealed that he suffers from the disease. Not in Jackson, he was not diagnosed until he was 52, and he is still alive today at the age of 67.
প্রকাশিত: 2025-10-25 10:22:00
উৎস: www.dailymail.co.uk
